Portal:Medicine

The Medicine Portal

The color fresco Care of The Sick by Domenico di Bartolo, 1441–1442, depicting the Santa Maria della Scala hospital in Siena, Italy

Medicine is the refined science and disciplined practice of tending to patients, encompassing the comprehensive management of diagnosis, prognosis, prevention, and treatment of their injuries or ailments, as well as the promotion of overall health and well-being. This field spans a diverse range of healthcare practices that have evolved over centuries, all with the objective of preserving and restoring health through the prevention and alleviation of illness.

Modern medicine draws extensively upon biomedical sciences, cutting-edge research, genetics, and advanced medical technologies to accurately diagnose, treat, and prevent disease and injury. Traditional approaches, such as pharmaceuticals and surgical intervention, are central to contemporary treatment; however, a wide array of therapies are also employed, including psychotherapy, external supports like splints and traction, medical devices, biologics, and ionizing radiation, among others. These varied methods form the foundation of medicine’s commitment to comprehensive care and innovation.

Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of creativity and skill), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, or an ancient philosopher and physician would apply bloodletting according to the theories of humorism. In recent centuries, since the advent of modern science, most medicine has become a combination of art and science (both basic and applied, under the umbrella of medical science). For example, while stitching technique for sutures is an art learned through practice, knowledge of what happens at the cellular and molecular level in the tissues being stitched arises through science. (Full article...)

Featured articles -

Featured articles are displayed here, which represent some of the best content on English Wikipedia.

---

• 
  
  

  

  Anti-FGM road sign near Kapchorwa, Uganda, 2004

  
  Female genital mutilation (FGM) (also known as female genital cutting, female genital mutilation/cutting (FGM/C) and female circumcision) is the cutting or removal of some or all of the vulva for non-medical reasons. FGM prevalence varies worldwide, but is majorly present in some countries of Africa, Asia and Middle East, and within their diasporas. As of 2024, UNICEF estimates that worldwide 230 million girls and women (144 million in Africa, 80 million in Asia, 6 million in Middle East, and 1-2 million in other parts of the world) had been subjected to one or more types of FGM.
  
  Typically carried out by a traditional circumciser using a blade, FGM is conducted from days after birth to puberty and beyond. In half of the countries for which national statistics are available, most girls are cut before the age of five. Procedures differ according to the country or ethnic group. They include removal of the clitoral hood (type 1-a) and clitoral glans (1-b); removal of the inner labia (2-a); and removal of the inner and outer labia and closure of the vulva (type 3). In this last procedure, known as infibulation, a small hole is left for the passage of urine and menstrual fluid, the vagina is opened for intercourse and opened further for childbirth. (Full article...)
• 
  
  

  

  Georges Gilles de la Tourette (1857–1904),
  namesake of Tourette syndrome

  
  Tourette syndrome or Tourette's syndrome (abbreviated as TS or Tourette's) is a common neurodevelopmental disorder that begins in childhood or adolescence. It is characterized by multiple movement (motor) tics and at least one vocal (phonic) tic. Common tics are blinking, coughing, throat clearing, sniffing, and facial movements. These are typically preceded by an unwanted urge or sensation in the affected muscles known as a premonitory urge, can sometimes be suppressed temporarily, and characteristically change in location, strength, and frequency. Tourette's is at the more severe end of a spectrum of tic disorders. The tics often go unnoticed by casual observers.
  
  Tourette's was once regarded as a rare and bizarre syndrome and has popularly been associated with coprolalia (the utterance of obscene words or socially inappropriate and derogatory remarks). It is no longer considered rare; about 1% of school-age children and adolescents are estimated to have Tourette's, though coprolalia occurs only in a minority. There are no specific tests for diagnosing Tourette's; it is not always correctly identified, because most cases are mild, and the severity of tics decreases for most children as they pass through adolescence. Therefore, many go undiagnosed or may never seek medical attention. Extreme Tourette's in adulthood, though sensationalized in the media, is rare, but for a small minority, severely debilitating tics can persist into adulthood. Tourette's does not affect intelligence or life expectancy. (Full article...)
• 
  
  

  

  High-resolution computed tomography images of the lower chest in a 16-year-old boy with diffuse panbronchiolitis

  
  Diffuse panbronchiolitis (DPB) is an inflammatory lung disease of unknown cause. It is a severe, progressive form of bronchiolitis, an inflammatory condition of the bronchioles (small air passages in the lungs). The term diffuse signifies that lesions appear throughout both lungs, while panbronchiolitis refers to inflammation found in all layers of the respiratory bronchioles (those involved in gas exchange). DPB causes severe inflammation and nodule-like lesions of terminal bronchioles, chronic sinusitis, and intense coughing with large amounts of sputum production.
  
  The disease is believed to occur when there is susceptibility, or a lack of immune system resistance, to DPB-causing bacteria or viruses, caused by several genes that are found predominantly in individuals of East Asian descent. The highest incidence occurs among Japanese people, followed by Koreans. DPB occurs more often in males and usually begins around age 40. It was recognized as a distinct new disease in the early 1960s and was formally named diffuse panbronchiolitis in 1969. (Full article...)
• 

  

  
  Amphetamine (contracted from alpha-methylphenethylamine) is a central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity; it is also used to treat binge eating disorder in the form of its inactive prodrug lisdexamfetamine. Amphetamine was discovered as a chemical in 1887 by Lazăr Edeleanu, and then as a drug in the late 1920s. It exists as two enantiomers: levoamphetamine and dextroamphetamine. Amphetamine properly refers to a specific chemical, the racemic free base, which is equal parts of the two enantiomers in their pure amine forms. The term is frequently used informally to refer to any combination of the enantiomers, or to either of them alone. Historically, it has been used to treat nasal congestion and depression. Amphetamine is also used as an athletic performance enhancer and cognitive enhancer, and recreationally as an aphrodisiac and euphoriant. It is a prescription drug in many countries, and unauthorized possession and distribution of amphetamine are often tightly controlled due to the significant health risks associated with recreational use.
  
  The first amphetamine pharmaceutical was Benzedrine, a brand which was used to treat a variety of conditions. Currently, pharmaceutical amphetamine is prescribed as racemic amphetamine, Adderall, dextroamphetamine, or the inactive prodrug lisdexamfetamine. Amphetamine increases monoamine and excitatory neurotransmission in the brain, with its most pronounced effects targeting the norepinephrine and dopamine neurotransmitter systems. (Full article...)
• 
  
  

  

  Buruli ulcer lesions. Top-left, an early ulcer. Top-right, a larger ulcer across the lower arm and wrist. Bottom, a large ulcer on the thigh.

  
  Buruli ulcer (/bəˈruːli/) is an infectious disease characterized by the development of painless open wounds. The disease is limited to certain areas of the world, most cases occurring in Sub-Saharan Africa and Australia. The first sign of infection is a small painless nodule or area of swelling, typically on the arms or legs. The nodule grows larger over days to weeks, eventually forming an open ulcer. Deep ulcers can cause scarring of muscles and tendons, resulting in permanent disability.
  
  Buruli ulcer is caused by skin infection with bacteria called Mycobacterium ulcerans. The mechanism by which M. ulcerans is transmitted from the environment to humans is not known, but may involve the bite of an aquatic insect or the infection of open wounds. Once in the skin, M. ulcerans grows and releases the toxin mycolactone, which blocks the normal function of cells, resulting in tissue death and immune suppression at the site of the ulcer. (Full article...)
• 

  

  Illustration of a SARS-CoV-2 virion

  
  
  A virus is a tiny infectious agent that reproduces inside the cells of living hosts. When infected, the host cell is forced to rapidly produce thousands of identical copies of the original virus. Unlike most living things, viruses do not have cells that divide; new viruses assemble in the infected host cell. But unlike simpler infectious agents like prions, they contain genes, which allow them to mutate and evolve. Over 4,800 species of viruses have been described in detail out of the millions in the environment. Their origin is unclear: some may have evolved from plasmids—pieces of DNA that can move between cells—while others may have evolved from bacteria.
  
  Viruses are made of either two or three parts. All include genes. These genes contain the encoded biological information of the virus and are built from either DNA or RNA. All viruses are also covered with a protein coat to protect the genes. Some viruses may also have an envelope of fat-like substance that covers the protein coat, and makes them vulnerable to soap. A virus with this "viral envelope" uses it—along with specific receptors—to enter a new host cell. Viruses vary in shape from the simple helical and icosahedral to more complex structures. Viruses range in size from 20 to 300 nanometres; it would take 33,000 to 500,000 of them, side by side, to stretch to 1 centimetre (0.4 in). (Full article...)
• 
  The 1966 New York City smog was a major air-pollution episode and environmental disaster, coinciding with that year's Thanksgiving holiday weekend. Smog covered the city and its surrounding area from November 23 to 26, filling the city's air with damaging levels of several toxic pollutants. It was the third major smog in New York City, following events of similar scale in 1953 and 1963.
  
  On November 23, a large mass of stagnant air over the East Coast trapped pollutants in the city's air. For three days, New York City was engulfed in dangerously high levels of carbon monoxide, sulfur dioxide, smoke, and haze. Pockets of air pollution pervaded the greater New York metropolitan area, including parts of New Jersey and Connecticut. By November 25, the smog became severe enough that regional leaders announced a "first-stage alert". During the alert, leaders of local and state governments asked residents and industry to take voluntary steps to minimize emissions. Health officials advised people with respiratory or heart conditions to remain indoors. The city shut off garbage incinerators, requiring massive hauling of garbage to landfills. A cold front dispersed the smog on November 26, and the alert ended. (Full article...)
• 
  
  

  

  Rolph, c. 1870

  
  John Rolph (4 March 1793 – 19 October 1870) was a Canadian physician, lawyer, and political figure. As a politician, he was considered the leader of the Reform faction in the 1820s and helped plan the Upper Canada Rebellion. As a doctor, he founded several medical schools and incorporated new teaching techniques and medical procedures into his lectures. However, his actions against rival medical schools decreased public confidence in the ability of medical professionals to regulate themselves.
  
  Rolph grew up in England and was educated in medicine and law. He immigrated to Upper Canada in 1813 and lived on his father's farm in Port Talbot, where he practiced law and medicine concurrently and opened a medical school called the Talbot Dispensary. In 1824, Rolph was elected to the Parliament of Upper Canada and returned to England to petition the Colonial Office to allow the naturalization of American citizens in Canada. He was elected as an alderman to Toronto's first city council, though he resigned after his council colleagues did not select him to be the city's mayor. (Full article...)
• 
  
  

  

  In 1942–43 the UK Government carried out extensive testing for oxygen toxicity in divers. The chamber is pressurised with air to 3.7 bar. The subject in the centre is breathing 100% oxygen from a mask.

  
  Oxygen toxicity is a condition resulting from the harmful effects of breathing molecular oxygen (O
  ₂) at increased partial pressures. Severe cases can result in cell damage and death, with effects most often seen in the central nervous system, lungs, and eyes. Historically, the central nervous system condition was called the Paul Bert effect, and the pulmonary condition the Lorrain Smith effect, after the researchers who pioneered the discoveries and descriptions in the late 19th century. Oxygen toxicity is a concern for underwater divers, those on high concentrations of supplemental oxygen, and those undergoing hyperbaric oxygen therapy.
  
  The result of breathing increased partial pressures of oxygen is hyperoxia, an excess of oxygen in body tissues. The body is affected in different ways depending on the type of exposure. Central nervous system toxicity is caused by short exposure to high partial pressures of oxygen at greater than atmospheric pressure. Pulmonary and ocular toxicity result from longer exposure to increased oxygen levels at normal pressure. Symptoms may include disorientation, breathing problems, and vision changes such as myopia. Prolonged exposure to above-normal oxygen partial pressures, or shorter exposures to very high partial pressures, can cause oxidative damage to cell membranes, collapse of the alveoli in the lungs, retinal detachment, and seizures. Oxygen toxicity is managed by reducing the exposure to increased oxygen levels. Studies show that, in the long term, a robust recovery from most types of oxygen toxicity is possible. (Full article...)
• 
  Genetics is the study of genes, genetic variation, and heredity in organisms. It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene.
  
  Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the context of a population. Genetics has given rise to a number of subfields, including molecular genetics, epigenetics, and population genetics. Organisms studied within the broad field span the domains of life (archaea, bacteria, and eukarya). (Full article...)
• 

  

  
  Bupropion, formerly called amfebutamone, and sold under the brand name Wellbutrin among others, is an atypical antidepressant primarily used to treat major depressive disorder and to support smoking cessation. It is also popular as an add-on medication in the cases of "incomplete response" to the first-line selective serotonin reuptake inhibitor (SSRI) antidepressant. Bupropion has several features that distinguish it from other antidepressants: it does not usually cause sexual dysfunction, it is not associated with weight gain and sleepiness, and it is more effective than SSRIs at improving symptoms of hypersomnia and fatigue. Bupropion, particularly the immediate release formulation, carries a higher risk of seizure than many other antidepressants, hence caution is recommended in patients with a history of seizure disorder. The medication is taken by mouth.
  
  
  Common adverse effects of bupropion with the greatest difference from placebo are dry mouth, nausea, constipation, insomnia, anxiety, tremor, and excessive sweating. Raised blood pressure is notable. Rare but serious side effects include seizures, liver toxicity, psychosis, and risk of overdose. Bupropion use during pregnancy may be associated with increased likelihood of congenital heart defects. (Full article...)
• 
  In the early 20th century, German researchers found additional evidence linking smoking to health harms, which strengthened the anti-tobacco movement in the Weimar Republic and led to a state-supported anti-smoking campaign. Early anti-tobacco movements grew in many nations from the middle of the 19th century. The 1933–1945 anti-tobacco campaigns in Nazi Germany have been widely publicized, although stronger laws than those passed in Germany were passed in some American states, the UK, and elsewhere between 1890 and 1930. After 1941, anti-tobacco campaigns were restricted by the Nazi government.
  
  The German movement was the most powerful anti-smoking movement in the world during the 1930s and early 1940s. However, tobacco control policy was incoherent and ineffective, with uncoordinated and often regional efforts by many actors. Obvious measures were not taken, and existing measures were not enforced. Some Nazi leaders condemned smoking and several of them openly criticized tobacco consumption, but others publicly smoked and denied that it was harmful. (Full article...)
• 

  

  Fluoridation does not affect the appearance, taste or smell of drinking water.

  
  
  Water fluoridation is the addition of fluoride to a public water supply to reduce tooth decay. Fluoridated water contains fluoride at a level that is effective for preventing cavities; this can occur naturally or by adding fluoride. Fluoridated water operates on tooth surfaces: in the mouth, it creates low levels of fluoride in saliva, which reduces the rate at which tooth enamel demineralizes and increases the rate at which it remineralizes in the early stages of cavities. Typically a fluoridated compound is added to drinking water, a process that in the U.S. costs an average of about $1.32 per person-year. Defluoridation is needed when the naturally occurring fluoride level exceeds recommended limits. In 2011, the World Health Organization suggested a level of fluoride from 0.5 to 1.5 mg/L (milligrams per litre), depending on climate, local environment, and other sources of fluoride. In 2024, the Department of Health and Human Services' National Toxicology Program found that water fluoridation levels above 1.5 mg/L are associated with lower IQ in children. In 2024, U.S. court rulings have raised concerns about the potential health risks of water fluoridation, including findings by the EPA and new risk assessments that suggest the benefits may be waning. Bottled water typically has unknown fluoride levels.
  
  
  Tooth decay remains a major public health concern in most industrialized countries, affecting 60–90% of schoolchildren and the vast majority of adults. Water fluoridation reduces cavities in children, while efficacy in adults is less clear. A Cochrane review estimates a reduction in cavities when water fluoridation was used by children who had no access to other sources of fluoride to be 35% in baby teeth and 26% in permanent teeth. Most European countries have experienced substantial declines in tooth decay, though milk and salt fluoridation is widespread in lieu of water fluoridation. Some studies suggest that water fluoridation, particularly in industrialized nations, may be unnecessary because topical fluorides (such as in toothpaste) are widely used, and caries rates have become low. (Full article...)
• 
  
  

  

  Thyrotoxic periodic paralysis occurs when the thyroid gland releases excessive amounts of thyroxine (thyroid hormone).

  
  Thyrotoxic periodic paralysis (TPP) is a rare condition featuring attacks of muscle weakness in the presence of hyperthyroidism (overactivity of the thyroid gland). Hypokalemia (a decreased potassium level in the blood) is usually present during attacks. The condition may be life-threatening if weakness of the breathing muscles leads to respiratory failure, or if the low potassium levels lead to abnormal heart rhythms. If untreated, it is typically recurrent in nature.
  
  The condition has been linked with genetic mutations in genes that code for certain ion channels that transport electrolytes (sodium and potassium) across cell membranes. The main ones are the L-type calcium channel α1-subunit and potassium inward rectifier 2.6; it is therefore classified as a channelopathy. The abnormality in the channel is thought to lead to shifts of potassium into cells, under conditions of high thyroxine (thyroid hormone) levels, usually with an additional precipitant. (Full article...)
• 
  
  

  

  Typical rash seen in dengue fever

  
  Dengue fever is a mosquito-borne disease caused by dengue virus, prevalent in tropical and subtropical areas. It is frequently asymptomatic; if symptoms appear they typically begin 3 to 14 days after infection. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin itching and skin rash. Recovery generally takes two to seven days. In a small proportion of cases, the disease develops into severe dengue (previously known as dengue hemorrhagic fever or dengue shock syndrome) with bleeding, low levels of blood platelets, blood plasma leakage, and dangerously low blood pressure.
  
  Dengue virus has four confirmed serotypes; infection with one type usually gives lifelong immunity to that type, but only short-term immunity to the others. Subsequent infection with a different type increases the risk of severe complications. The symptoms of dengue resemble many other diseases including malaria, influenza, and Zika. Blood tests are available to confirm the diagnosis including detecting viral RNA, or antibodies to the virus. (Full article...)

Selected image –

A sperm attempts to penetrate the ovum coat to fertilize it.

WikiProject

Get involved by joining WikiProject Medicine. We discuss collaborations and all manner of issues on our talk page.

Related portals

Good articles -

These are Good articles, which meet a core set of high editorial standards.

---

• 
  Willis John Potts (March 22, 1895 – May 5, 1968) was an American pediatric surgeon and one of the earliest physicians to focus on the surgical treatment of heart problems in children. Potts set up one of the country's first pediatric surgery programs at Children's Memorial Hospital (later renamed Lurie Children's Hospital) in Chicago.
  
  A graduate of the University of Chicago and Rush Medical College, Potts was known for introducing a surgery to address the heart defects that resulted in blue baby syndrome; the procedure became known as the Potts shunt. In addition, Potts performed the first successful repair of a cardiovascular abnormality known as a pulmonary artery sling. He also invented several surgical instruments, with a particular emphasis on devices used in surgery on major blood vessels. (Full article...)
• 
  
  

  

  An Operation at the Military Hospital, Endell Street - Dr L Garrett, Dr Flora Murray, Dr W Buckley, Francis Dodd, 1920. Imperial War Museum, London.

  
  Endell Street Military Hospital was a First World War military hospital located on Endell Street in Covent Garden, central London. The hospital was substantially staffed by suffragists (women who supported the introduction of votes for women).
  
  The medical pioneers Flora Murray and Louisa Garrett Anderson recruited enough medically trained women to staff an entire hospital in France at the beginning of the war that was in operation from 1914 to 1915. Drawing experience and staff of this hospital, the Endell Street hospital was established in London as a RAMC hospital under the War department in May 1915 by Murray and Anderson. The Endell hospital had 573 beds, allowing for some 26,000 patients to be cared for during the five years it was active. The hospital closed shortly after the end of the war in December 1919. (Full article...)
• 

  

  
  Martha Maria "Mattie" Hughes Cannon (July 1, 1857 – July 10, 1932) was a British-American politician, physician, Utah women's rights advocate, suffragist, and a polygamous wife engaged in polygyny. Her family immigrated to the United States as converts to the Church of Jesus Christ of Latter-day Saints (LDS Church) and traveled West to settle in the Utah territory with other church members. She started working at the age of fourteen, and at sixteen she enrolled in the University of Deseret (now called the University of Utah), receiving a bachelor's degree in Chemistry. She later attended the University of Michigan and received an M.D.. She became the fourth of six wives in a polygamous marriage to Angus M. Cannon, a prominent Latter-day Saint leader during the anti-polygamy crusade. Cannon exiled herself to Europe so she wouldn't have to testify against her husband and others. Upon returning to Utah, Cannon worked as a doctor and fought for women's rights. She helped put women enfranchisement into Utah's constitution when it was granted statehood in 1896. On November 3, 1896, Cannon became the first female state senator elected in the United States, defeating her own husband, who was also on the ballot. Cannon was the author of Utah sanitation laws and was a founder and member of Utah's first State Board of Health. (Full article...)
• 
  
  

  

  Foster Herben aged around 23

  
  George Foster Herben (17 March 1893 – 17 March 1966) was an American physician. He spent his career in New York, predominantly treating tuberculosis. After interning at Brooklyn Hospital, Herben worked at the Loomis Sanitarium by Liberty, and then at the House of Rest at Sprain Ridge, a tuberculosis hospital and preventorium in Yonkers. At the House of Rest he variously served as physician in chief and as medical director. Herben developed and published several new treatments during this time, including a replacement for conventional iron lungs.
  
  Herben was the son of Stephen J. Herben and Grace Foster Herben, a Methodist minister and missionary, respectively. His father's influence occasioned a number of high-profile acquaintances, from meeting President Theodore Roosevelt as a boy to knowing his father's friend Thomas Edison. He was the older brother of Stephen J. Herben Jr., a professor of philology at Bryn Mawr College. (Full article...)
• 

  

  A fish parasite, the isopod Cymothoa exigua, replacing the tongue of a Lithognathus

  
  
  Parasitism is a close relationship between species, where one organism, the parasite, lives on or inside another organism, the host, causing it some harm, and is adapted structurally to this way of life. The entomologist E. O. Wilson characterised parasites as "predators that eat prey in units of less than one". Parasites include single-celled protozoans such as the agents of malaria, sleeping sickness, and amoebic dysentery; animals such as hookworms, lice, mosquitoes, and vampire bats; fungi such as honey fungus and the agents of ringworm; and plants such as mistletoe, dodder, and the broomrapes.
  
  There are six major parasitic strategies of exploitation of animal hosts, namely parasitic castration, directly transmitted parasitism (by contact), trophically-transmitted parasitism (by being eaten), vector-transmitted parasitism, parasitoidism, and micropredation. One major axis of classification concerns invasiveness: an endoparasite lives inside the host's body; an ectoparasite lives outside, on the host's surface. (Full article...)
• 

  

  
  Vitamin A is a fat-soluble vitamin that is an essential nutrient. The term "vitamin A" encompasses a group of chemically related organic compounds that includes retinol, retinyl esters, and several provitamin (precursor) carotenoids, most notably β-carotene (beta-carotene). Vitamin A has multiple functions: growth during embryo development, maintaining the immune system, and healthy vision. For aiding vision specifically, it combines with the protein opsin to form rhodopsin, the light-absorbing molecule necessary for both low-light (scotopic vision) and color vision.
  
  Vitamin A occurs as two principal forms in foods: A) retinoids, found in animal-sourced foods, either as retinol or bound to a fatty acid to become a retinyl ester, and B) the carotenoids α-carotene (alpha-carotene), β-carotene, γ-carotene (gamma-carotene), and the xanthophyll beta-cryptoxanthin (all of which contain β-ionone rings) that function as provitamin A in herbivore and omnivore animals which possess the enzymes that cleave and convert provitamin carotenoids to retinol. Some carnivore species lack this enzyme. The other carotenoids do not have retinoid activity. (Full article...)
• 
  
  

  

  3D structure of major prion protein

  
  A prion /ˈpriːɒn/ is a misfolded protein that induces misfolding in normal variants of the same protein, leading to cellular death. Prions are responsible for prion diseases, known as transmissible spongiform encephalopathy (TSEs), which are fatal and transmissible neurodegenerative diseases affecting both humans and animals. These proteins can misfold sporadically, due to genetic mutations, or by exposure to an already misfolded protein, leading to an abnormal three-dimensional structure that can propagate misfolding in other proteins.
  
  The term prion comes from "proteinaceous infectious particle". Unlike other infectious agents such as viruses, bacteria, and fungi, prions do not contain nucleic acids (DNA or RNA). Prions are mainly twisted isoforms of the major prion protein (PrP), a naturally occurring protein with an uncertain function. They are the hypothesized cause of various TSEs, including scrapie in sheep, chronic wasting disease (CWD) in deer, bovine spongiform encephalopathy (BSE) in cattle (mad cow disease), and Creutzfeldt–Jakob disease (CJD) in humans. (Full article...)
• 
  Nasodigitoacoustic syndrome, also called Keipert syndrome, is a rare congenital syndrome first described by J.A. Keipert and colleagues in 1973. The syndrome is characterized by a misshaped nose, broad thumbs and halluces (the big toes), brachydactyly, sensorineural hearing loss, facial features such as hypertelorism (unusually wide-set eyes), and developmental delay.
  
  It is believed to be inherited in an X-linked recessive manner, which means a genetic mutation causing the disorder is located on the X chromosome, and while two copies of the mutated gene must be inherited for a female to be born with the disorder, just one copy is sufficient to cause a male to be born with the disorder. Nasodigitoacoustic syndrome is likely caused by a mutated gene located on the X chromosome between positions Xq22.2–q28. (Full article...)
• 

  

  A 1776 textbook drawing of a tobacco smoke enema device, consisting of a nozzle, a fumigator and a bellows

  
  The tobacco smoke enema, an insufflation of tobacco smoke into the rectum by enema, was a medical treatment employed by European physicians for a range of ailments.
  
  Tobacco was recognised as a medicine soon after it was first imported from the New World, and tobacco smoke was used by Western medical practitioners as a tool against cold and drowsiness, but applying it by enema was a technique learned from the North American indigenous peoples. The procedure was used to treat gut pain, and attempts were often made to resuscitate victims of near drowning. Liquid tobacco enemas were often given to ease the symptoms of a hernia. (Full article...)
• 

  

  A Book of Medical Discourses (1883) by Rebecca Lee Crumpler, M.D.

  
  Rebecca Lee Crumpler (born Rebecca Davis, February 8, 1831 – March 9, 1895) was an American physician, nurse and author. After studying at the New England Female Medical College, in 1864 she became the first African American woman to become a doctor of medicine in the United States. Crumpler was also one of the first female physician authors in the nineteenth century. In 1883, she published A Book of Medical Discourses. The book has two parts that cover the prevention and cure of infantile bowel complaints, and the life and growth of human beings. Dedicated to nurses and mothers, it focuses on maternal and pediatric medical care and was among the first publications written by an African American on the subject of medicine.
  
  Crumpler graduated from medical college at a time when very few African Americans were permitted to attend medical college or publish books. Crumpler first practiced medicine in Boston, primarily serving poor women and children. After the American Civil War ended in 1865, she moved to Richmond, Virginia, believing treating women and children was an ideal way to perform missionary work. Crumpler worked for the Freedmen's Bureau to provide medical care for freedmen and freedwomen. (Full article...)
• 
  
  

  

  Formation of wheals on the arm

  
  Solar urticaria (SU) is a rare condition in which exposure to ultraviolet or UV radiation, or sometimes even visible light, induces a case of urticaria or hives that can appear in both covered and uncovered areas of the skin. It is classified as a type of physical urticaria. The classification of disease types is somewhat controversial. One classification system distinguished various types of SU based on the wavelength of the radiation that causes the breakout; another classification system is based on the type of allergen that initiates a breakout.
  
  The agent in the human body responsible for the reaction to radiation, known as the photoallergen, has not yet been identified. The disease itself can be difficult to diagnose properly because it is so similar to other dermatological disorders, such as polymorphous light eruption or PLE. The most helpful test is a diagnostic phototest, a specialized test which confirms the presence of an abnormal sunburn reaction. Once recognized, treatment of the disease commonly involves the administration of antihistamines, and desensitization treatments such as phototherapy. In more extreme cases, the use of immunosuppressive drugs and even plasmapheresis may be considered. (Full article...)
• 

  

  Prevalence of HIV/AIDS in adult (ages 15–49) populations (1999–2002)

  
  As of 2012, approximately 1,100,000 people in Malawi are HIV-positive, which represents 10.8% of the country's population. Because the Malawian government was initially slow to respond to the epidemic under the leadership of Hastings Banda (1966–1994), the prevalence of HIV/AIDS increased drastically between 1985, when the disease was first identified in Malawi, and 1993, when HIV prevalence rates were estimated to be as high as 30% among pregnant women. The Malawian food crisis in 2002 resulted, at least in part, from a loss of agricultural productivity due to the prevalence of HIV/AIDS. Various degrees of government involvement under the leadership of Bakili Muluzi (1994–2004) and Bingu wa Mutharika (2004–2012) resulted in a gradual decline in HIV prevalence, and, in 2003, many people living in Malawi gained access to antiretroviral therapy. Condoms have become more widely available to the public through non-governmental organizations, and more Malawians are taking advantage of HIV testing services.
  
  Due to several successful television and radio campaigns by the Malawian government and non-governmental organizations in Malawi, levels of awareness regarding HIV/AIDS are high among the general population. However, many men have adopted fatalistic attitudes in response to the epidemic, convincing themselves that death from AIDS is inevitable; on the other hand, some have implemented preventive techniques such as partner selection to try to reduce their risk of infection. Although many women have developed strategies to protect themselves from HIV, women are more likely to be HIV-positive than men in Malawi. The epidemic has affected sexual relationships between partners, who must cooperate to protect themselves from the disease. In addition, many teachers exclude HIV/AIDS from their curricula because they are uncomfortable discussing the topic or because they do not feel knowledgeable about the issue, and, therefore, many children are not exposed to information about HIV/AIDS at school. Finally, the epidemic has produced significant numbers of orphans in Malawi, leaving children vulnerable to abuse and exploitation. (Full article...)
• 
  
  

  

  Canker sore on the lower lip

  
  Aphthous stomatitis, or recurrent aphthous stomatitis (RAS), commonly referred to as a canker sore, is a common condition characterized by the repeated formation of benign and non-contagious mouth ulcers (aphthae) in otherwise healthy individuals.
  
  The cause is not completely understood but involves a T cell-mediated immune response triggered by a variety of factors which may include nutritional deficiencies, local trauma, stress, hormonal influences, allergies, genetic predisposition, certain foods, dehydration, some food additives, or some hygienic chemical additives like SDS (common in toothpaste). (Full article...)
• 
  
  

  

  This is an image of an asthmatics airways, it become swollen and full of mucous.

  
  Asthma is a long-term inflammatory disease of the airways of the lungs. It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. Symptoms include episodes of wheezing, coughing, chest tightness, and shortness of breath. These may occur a few times a day or a few times per week. Depending on the person, asthma symptoms may become worse at night or with exercise.
  
  
  Asthma is thought to be caused by a combination of genetic and environmental factors. Environmental factors include exposure to air pollution and allergens. Other potential triggers include medications such as aspirin and beta blockers. Diagnosis is usually based on the pattern of symptoms, response to therapy over time, and spirometry lung function testing. Asthma is classified according to the frequency of symptoms of forced expiratory volume in one second (FEV₁), and peak expiratory flow rate. It may also be classified as atopic or non-atopic, where atopy refers to a predisposition toward developing a type 1 hypersensitivity reaction. (Full article...)
• 
  Anna Elisabeth Johansson Bågenholm (born 1970) is a Swedish radiologist from Vänersborg, who survived after a skiing accident in 1999 left her trapped under a layer of ice for 80 minutes in freezing water. During this time she experienced extreme hypothermia and her body temperature decreased to 13.7 °C (56.7 °F), one of the lowest survived body temperatures ever recorded in a human with accidental hypothermia. Bågenholm was able to find an air pocket under the ice, but experienced circulatory arrest after 40 minutes in the water.
  
  After rescue, Bågenholm was transported by helicopter to the Tromsø University Hospital, where a team of more than a hundred doctors and nurses worked in shifts for nine hours to save her life. Bågenholm woke up ten days after the accident, paralyzed from the neck down and subsequently spent two months recovering in an intensive care unit. Although she has made an almost full recovery from the incident, late in 2009 she was still having minor symptoms in hands and feet related to nerve injury. Bågenholm's case has been discussed in the leading British medical journal The Lancet, and in medical textbooks. (Full article...)

Did you know –

• ...Peyer's patches are an example of gut-associated lymphoid tissue?

• ...the brain itself is not sensitive to pain, because it lacks pain-sensitive nerve fibers? Several areas of the head can hurt, including a network of nerves which extends over the scalp and certain nerves in the face, mouth, and throat.
• ...that irritable bowel syndrome (IBS) may sometimes have an acute onset and develop after an infectious illness, and that this "Post infectious IBS" (IBS-PI) is drawing much clinical investigation?

General images –

The following are images from various Medicine-related articles on Wikipedia.

• 
  The plinthios brochos as described by Greek physician Heraklas, a sling for binding a fractured jaw. These writings were preserved in one of Oribasius' collections. (from History of medicine)
• 
  Total healthcare cost per person. Public and private spending. US dollars PPP. For example: $6,319 for Canada in 2022. $12,555 for the US in 2022. (from Health care)
• 
  A Ukrainian monument to the HIV pandemic. (from History of medicine)
• 
  Sometimes traditional medicines include parts of endangered species, such as the slow loris in Southeast Asia. (from Traditional medicine)
• 
  The Quaker-run York Retreat, founded in 1796, gained international prominence as a centre for moral treatment and a model of asylum reform following the publication of Samuel Tuke's Description of the Retreat (1813). (from History of medicine)
• 
  A cuneiform terracotta tablet describing a medicinal recipe for poisoning (c. 18th century BCE). Discovered in Nippur, Iraq.
• 
  Infographic showing how healthcare data flows within the billing process (from Medical billing)
• 
  Life expectancy vs healthcare spending of rich OECD countries. US average of $10,447 in 2018. (from Health care)
• 
  Hippocrates (c. 460–370 BCE). Known as the "father of medicine". (from History of medicine)
• 
  A cochlear implant is a common kind of neural prosthesis, a device replacing part of the human nervous system. (from History of medicine)
• 
  Smallpox vaccination in Niger, 1969. A decade later, this was the first infectious disease to be eradicated. (from History of medicine)
• 
  Mexico City epidemic of 1737, with elites calling on the Virgin of Guadalupe (from History of medicine)
• 
  Medical personnel place sterilized covers on the arms of the daVinci Xi surgical system, a minimally-invasive robotic surgery system, at the William Beaumont Army Medical Center. (from History of medicine)
• 
  Statue of Robert Koch, father of medical bacteriology, at Robert-Koch-Platz (Robert Koch square) in Berlin (from History of medicine)
• 
  Botánicas such as this one in Jamaica Plain, Boston, cater to the Latino community and sell folk medicine alongside statues of saints, candles decorated with prayers, lucky bamboo, and other items. (from Traditional medicine)
• 
  The numbers of Americans lacking health insurance and the uninsured rate from 1987 to 2008 (from Health insurance)
• 
  A Neo-Assyrian cuneiform tablet fragment describing medical text (c. 9th to 7th century BCE). (from History of medicine)
• 
  Jackson Memorial Hospital in Miami, the primary teaching hospital of the University of Miami's Miller School of Medicine and the largest hospital in the United States with 1,547 beds (from Health care)
• 
  Seven named physicians and botanists of the Classical world from Vienna Dioscurides. Clockwise from top center: Galen, Dioscorides, Nicander, Rufus of Ephesus, Andreas of Carystus, Apollonius Mus or of Pergamon, Crateuas (from History of medicine)
• 
  Guy's Hospital in 1820 (from History of medicine)
• 
  Curandera performing a limpieza in Cuenca, Ecuador (from Traditional medicine)
• 
  Yarrow, a medicinal plant found in human-occupied caves in the Upper Palaeolithic period. (from History of medicine)
• 
  Magical stela or cippus of Horus inscribed with healing encantations (c. 332 to 280 BCE). (from History of medicine)
• 
  "More Doctors Smoke Camels than Any Other Cigarette" advertisement for Camel cigarettes in the 1940s (from Medical ethics)
• 
  Global concentrations of health care resources, as depicted by the number of physicians per 10,000 individuals, by country. Data is sourced from a World Health Statistics 2010, a WHO report. (from Health care)
• 
  Life Expectancy of the total population at birth among several OECD member nations. Data source: OECD's iLibrary (from Health insurance)
• 
  Zhang Zhongjing – a Chinese pharmacologist, physician, inventor, and writer of the Eastern Han dynasty. (from History of medicine)
• 
  Most countries have seen a tremendous increase in life expectancy since 1945. However, in southern Africa, the HIV epidemic beginning around 1990 has eroded national health. (from History of medicine)
• 
  Primary care may be provided in community health centers. (from Health care)
• 
  Taoist symbol of Yin and Yang (from Medical ethics)
• 
  Replica of Antonie van Leeuwenhoek's microscope of the 1670s (from History of medicine)
• 
  Medicine during the First World War - Medical Transport. (from History of medicine)
• 
  "Diagram of the causes of mortality in the army in the East" by Florence Nightingale. (from History of medicine)
• 
  Health Expenditure per capita (in PPP-adjusted US$) among several OECD member nations. Data source: OECD's iLibrary (from Health insurance)
• 
  Health spending by country. Percent of GDP (Gross domestic product). For example: 11.2% for Canada in 2022. 16.6% for the United States in 2022. (from Health care)
• 
  American combat surgery during the Pacific War, 1943 (from History of medicine)
• 
  American Civil War hospital at Gettysburg, 1863 (from History of medicine)
• 
  Sketch of Muslim physician Muhammad ibn Zakariya al-Razi (from History of medicine)
• 
  COVID-19 swab testing in Rwanda (2021). (from History of medicine)
• 
  Galen (129–216 CE), known for his wide insights into anatomy. (from History of medicine)
• 
  Ethical prayer for medical wisdom by Dr Edmond Fernandes (from Medical ethics)
• 
  Depiction of smallpox in Franciscan Bernardino de Sahagún's history of the conquest of Mexico, Book XII of the Florentine Codex, from the defeated Aztecs' point of view (from History of medicine)
• 
  A 12th-century Byzantine manuscript of the Hippocratic Oath (from Medical ethics)
• 
  18th-century medical remedies collected by a British Gentry family (from History of medicine)
• 
  A doctor checks a patient's pulse in Meiji-era Japan. (from History of medicine)
• 
  healthcare expenditure in Japan by age group (from Health insurance)
• 
  An American billing clerk preparing a detailed invoice. (1992) (from Medical billing)
• 
  The emergency room is often a frontline venue for the delivery of primary medical care. (from Health care)
• 
  Emil Kraepelin (1856–1926), the founder of modern scientific psychiatry, psychopharmacology and psychiatric genetics. (from History of medicine)
• 
  Louis Pasteur experimenting on bacteria, c. 1870 (from History of medicine)
• 
  Charite in Berlin (from History of medicine)
• 
  National Hospital for Neurology and Neurosurgery in London, United Kingdom is a specialist neurological hospital. (from Health care)
• 
  The Edwin Smith Surgical Papyrus, written in the 17th century BCE, contains the earliest recorded reference to the brain. New York Academy of Medicine. (from History of medicine)
• 
  AMA Code of Medical Ethics (from Medical ethics)
• 
  Patient, Surrey County Lunatic Asylum, c. 1850–58. The asylum population in England and Wales rose from 1,027 in 1827 to 74,004 in 1900. (from History of medicine)
• 
  Traditional medicine in a market in Antananarivo, Madagascar (from Traditional medicine)
• 
  A 12th-century manuscript of the Hippocratic Oath in Greek, one of the most famous aspects of classical medicine that carried into later eras (from History of medicine)
• 
  Hospital train "Therapist Matvei Mudrov" in Khabarovsk, Russia (from Health care)
• 
  Mandrake (written 'ΜΑΝΔΡΑΓΟΡΑ' in Greek capitals). Naples Dioscurides, 7th century (from History of medicine)

More Did you know (auto generated)

• ... that fourteenth-century Buddhist monk Tuệ Tĩnh is referred to as a founding father of traditional Vietnamese medicine?
• ... that Tang Zonghai was one of the first advocates for the integration of Chinese and Western medicine?
• ... that a lack of screening for pregnant women with syphilis in sub-Saharan Africa is associated with increased infant mortality?
• ... that the Noongar used the Eucalyptus wandoo tree as a medicine and ointment?
• ... that Constance Fozzard was told during her surgical training that women with children could not become consultants?
• ... that the Anglo-Saxons may have used a mixture of garlic, another Allium, wine, and bovine bile as an eye medicine?

Topics

Categories

• Medicine

Category puzzle

Select [►] to view subcategories

Medicine

Medicine by city

Medicine by country

Medicine by country subdivision

Medicine by dependent territory

Medicine by century

Medicine by decade

Medicine by year

Alternative medicine

Clinical medicine

Veterinary medicine

Medical lists

Works about medicine

Medical activism

Medical associations

Cause (medicine)

Chemicals in medicine

Health-related conspiracy theories

Medical culture

Medical education

History of medicine

Intersex and medicine

Medical aspects of death

Medical diplomacy

Medical families

Medical humanities

Medical monitoring

Medical phenomena

Medical prevention

Medical volunteerism

Medical and health organizations

Practice of medicine

Prescription of drugs

Religion and medicine

Medical research

Medicine in society

Medical symbols

Medical technology

Medical terminology

Theory of medicine

Women in medicine

Medicine stubs

• Health
  Clinical research
• Disability
• Diseases and disorders
• Therapy

• Biology
  Anatomy
• Biological engineering
• Bioethics
• Cell biology
• Microbiology
• Physiology

Recognized content

Associated Wikimedia

The following Wikimedia Foundation sister projects provide more on this subject:

• 

  Commons
  Free media repository

• 

  Wikibooks
  Free textbooks and manuals

• 

  Wikidata
  Free knowledge base

• 

  Wikinews
  Free-content news

• 

  Wikiquote
  Collection of quotations

• 

  Wikisource
  Free-content library

• 

  Wikiversity
  Free learning tools

• 

  Wiktionary
  Dictionary and thesaurus

Discover Wikipedia using portals

• 

  List of all portals

• 

  The arts portal

• 

  Biography portal

• 

  Current events portal

• 

  Geography portal

• 

  History portal

• 

  Mathematics portal

• 

  Science portal

• 

  Society portal

• 

  Technology portal

• 

  Random portal

• 

  WikiProject Portals